CYBA Antikörper (AA 21-120)

Produktnummer ABIN750538

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CYBA in WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für CYBA Antikörper (AA 21-120) (ABIN750538)

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CYBA Antikörper

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CK18 Cytochrome b245 Light Chain/p22phox

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CYBA Antikörper (ABIN750538)

Song, Zhang, Han, Zhang, Zhang, Gao, Zhang, Chu, Zhao: "Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 945-956, (2019) (PubMed).

Yue, Wang, Wang, Du, Shen, Tang, Wang, Yin: "Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflammation via NOX4 and TLR2 pathways." in: International journal of biological macromolecules, Vol. 89, pp. 376-88, (2016) (PubMed).

Yoshida, Murayama, Kawashima, Nagahara, Kangawa, Mizukami, Kimura, Abe, Hayashi, Shibutani: "Apocynin and enzymatically modified isoquercitrin suppress the expression of a NADPH oxidase subunit p22phox in steatosis-related preneoplastic liver foci of rats." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, Vol. 69, Issue 1, pp. 9-16, (2016) (PubMed).

Li, Wang, Zhu, Zhang, Pan, Wang et al.: "Arctigenin suppresses transforming growth factor-?1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen ..." in: Free radical research, Vol. 49, Issue 9, pp. 1095-113, (2015) (PubMed).

Walton, Shin, Tajinda, Heusner, Kogan, Miyake, Chen, Tamura, Matsumoto: "Adult neurogenesis transiently generates oxidative stress." in: PLoS ONE, Vol. 7, Issue 4, pp. e35264, (2012) (PubMed).

Details zu CYBA

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Andere Bezeichnung: Cytochrome b245 Light Chain

Hintergrund:

Synonyms: p22-PHOX, Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22phox, CYBA

Background: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Gen-ID: 1535

UniProt: P13498

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis